the role of insulators

Shandong Zibo Electric Porcelain Factory Co., Ltd. specializes in producing post insulators, the role of insulators is directional, which is found in the fruit fly experiment. The insertion of the transposon gypsy on the yellow locus y of D. melanogaster resulted in inactivation of the y gene in some tissues, but the y gene remained active in some tissues due to one end of the transposon gypsy There is an insulator sequence. When gypsy is inserted at different positions of the & quot; locus & quot; there is a different effect on the activity of the gene. This is because the activity of the y gene is regulated by four enhancers that block the activation of the gene in the wing blade and the body cuticle when the insulator is inserted just upstream of the promoter But not blocking the expression of the y gene in the tissues of bristles and farsal claws (from the downstream enhancers).

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